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👐 Unlock the power of 24-hour hydration with zero grease—your hands’ new best friend!
Prequel Skin Hand Cream is a dermatologist-developed, clinically tested moisturizer designed for dry, cracked hands. Featuring lipid layer enhancers and a proprietary water-resistant film former, it delivers 24-hour hydration and protection even after frequent handwashing. Its lightweight, fragrance-free formula absorbs quickly without greasiness, making it ideal for all skin types and professionals who demand lasting care on the go.













| ASIN | B0CYDGC42H |
| Active Ingredients | Lipid Layer Enhancers |
| Age Range (Description) | Adult |
| Age Range Description | Adult |
| Best Sellers Rank | #11,494 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #38 in Hand Creams & Lotions |
| Brand | Prequel |
| Brand Name | Prequel |
| Country as Labeled | United States |
| Customer Reviews | 4.4 out of 5 stars 790 Reviews |
| Item Form | Lotion |
| Item Volume | 3.4 fluid ounces |
| Manufacturer | Prequel Skin |
| Material Features | Allergy Tested |
| Material Type Free | Fragrance Free |
| Number of Items | 1 |
| Other Special Features of the Product | Lightweight |
| Product Benefits | Creates flexible film to prevent water loss and dryness. |
| Recommended Uses For Product | Help prevent moisture loss by using after hand washing. |
| Scent Name | Fragrance Free |
| Skin Type | All, Dry, Normal, Oily, Sensitive |
| Special Feature | Lightweight |
| Special Ingredients | Lipid Layer Enhancers |
| Specific Uses For Product | Dryness |
| Target Use Body Part | Hands |
| UPC | 810129110203 |
| Unit Count | 3.4 Fluid Ounces |
O**E
Keeps My Hands Feeling Soft and Protected
This hand cream has earned a permanent spot on my desk, and I use it multiple times throughout the day. My hands tend to get irritated easily, especially during the colder months, so I'm always looking for something that provides lasting moisture without feeling heavy. What I like most is that it seems to create a protective layer on my skin that doesn't immediately disappear after washing my hands. My hands continue to feel comfortable and moisturized even after getting them wet, which isn't something I've experienced with many other hand creams. The formula is thick enough to feel nourishing, but it doesn't leave behind a greasy or sticky residue. I can apply it and get right back to typing, using my phone, or handling paperwork without feeling like I need to wipe my hands off first. I also appreciate that it's unscented, absorbs well, and leaves my skin feeling soft and smooth. A little goes a long way, so the tube lasts quite a while even with daily use. If you're looking for a hand cream that provides lasting moisture without the greasy feel, this one is definitely worth trying.
G**E
Moisturizing Cream
Love this cream. Moisturizes hands and cracked feet. Slight fragrance, lightweight cream and smooth consistency. Great value for the money.
L**A
Amazing
Love this hand cream! I will buy it again, not greasy and makes my hands feel so soft.
M**E
Good hand cream
This hand cream is different than any I’ve used before. It comes in a larger tube than I expected, and I felt like it was a great value for the money. It’s very lightweight, and it doesn’t leave your hands feeling greasy or slimy. I love the way it dries down. For this reason, though, it doesn’t feel quite as moisturizing as some other creams. It does protect your hands when you wash them later, so that’s a trade off. I will definitely repurchase.
S**R
The only hand cream worth buying
This is the best hand cream we have ever used. It is light but hydrating and long lasting. My hubby has eczema on his hands which is aggravated from washing. Using this regularly has healed his skin. Such great value for money. Smells good too. (I have used this on my face, but ask your dermo before copying me)
M**A
Prequel hand lotion.
Love the feel of this lotion. Not greasy and definitely moisturizes.
P**E
Meh EDIT: DON’T DO IT
EDIT: Removed a star for a full 1 star review because this tastes absolutely rancid. Before I start: no, I do not eat my hand creams. However, it’s natural for me to apply hand cream and then go about my day. This can include picking up things to put into my mouth or on my lips like medications or chips or lip balm (in a pot you need to dig your finger into). In the days I’ve had this hand cream, I’ve been tasting an absolutely foul, bitter taste in my mouth. It’s not your run of the mill bitterness. It’s the kind where I gag and automatically run to spit and rinse and mouth because my brain thinks I’m going to die if I swallow. It tastes dreadful. I can’t even begin to describe how disgusting this is. I blamed my medications at first, but I’ve been taking those for a long time, and this hand cream is the newest edition to my life. After trial and error, I’m sure that it’s the hand cream that’s causing this. So it doesn’t even matter if the whole “apply it, rub it until it thickens and turns velvety so the film forms, and then you don’t have to worry about reapplying for hours!” thing works. You MUST wash this off your hands completely before doing mundane things like eating chips or putting medication into your mouth unless you want to taste something indescribably horrible thanks to the residue left on your fingers from this product. PREVIOUS 2 STAR REVIEW: Texture: it’s extremely thin and watery. It spreads very nicely. Scent: none Greasiness: maybe I’m just really sensitive to sensations, but I find that this is greasy. I’m the kind of person who absolutely hates anything on my palms/fingertips, so if I just apply some on the back of my hands and rub them together, it’s fine. However if I apply it the traditional way by putting some in my palm and then rubbing my hands together that way, it is quite greasy. I can’t really touch anything afterward or else it’ll just be really slick and things will slip out of my hands, and there’s a residue on my phone screen. Even if I let it sit for five minutes, it doesn’t fully absorb and it’s still greasy on my palms and fingertips, which is exactly what the marketing said wouldn’t happen, so I deducted a star there. Moisturizing factor: to be fair, I have extremely dry, cracked hands from psoriasis that are so bad that I’m bleeding on the back of my hands. I’ve been desperately searching for a hand cream to give me some relief. On the spots that aren’t really affected by psoriasis, I think it’s decently moisturizing but nothing that something cheaper like Lubriderm or O’ Keefe’s can’t do for you. On my psoriasis-affected spots, I do get some visible relief, but once I touch my hands it still feels scaly and dry. Maybe if you just need normal hydration, this will probably be enough for you. The film former: doesn’t work for me. Again, I have aggressively dry hands because of a medical issue and not just normal dry skin or winter-related dry skin. I do notice that as I wash my hands after using this, it does feel like there’s some sort of film on my hands. However, after drying them (only by lightly dabbing and not swiping a towel across my hands), it’s completely gone and I have to reapply. It’s like this 5 minutes after applying and 1 hour after applying, so I don’t think the set down time matters. I can’t speak for how this would work on “normal” hands, but for me this was nothing more than gimmicky marketing that doesn’t really work in the long term. I watched through the promotional videos and reviews for a tutorial because I’m highly aware that this may be user error, and I wanted to give it a fair shot. Still, I didn’t find anything unique or innovative about this. This was not worth the $12 I spent while it was on sale. I’ll be using it up just so it doesn’t go to waste and then moving on to find a different hand cream.
E**L
Works great to soften and moisturize skin
One of the few creams that does what it says. Works well to keep dry and cracked skin soft when used regularly.
A**R
No!
Not recommended. Leaves my hands feeling dry and flakes as well.
L**L
Reasonable but not remarkable
Good moisturizer but nothing better than cheaper ones I've bought locally. I'd give it 7/10 in all areas
B**N
Did not suit me
It didn’t moisturise my hands. In fact , my hands felt drier than when I used cheaper ones. I definitely WONT be buying again.
Trustpilot
2 months ago
3 weeks ago