How does TYLENOL work?

Tylenol contains the active ingredient acetaminophen, which is a pain reliever and fever reducer. It works by elevating the body's overall pain threshold so you feel less pain, and lowers your fever by helping your body eliminate excess heat.

What can I take for a headache?

Headaches can disrupt your day and finding quick, reliable relief matters. TYLENOL is a common option for many headache types and is gentle on the stomach. Use products only as directed.

Pain relief for arthritis?

Arthritis pain can be challenging. TYLENOL is a pain relief option for minor pains of arthritis. TYLENOL® 8HR Arthritis features extended-release, bi-layer caplet design for powerful pain relief that lasts up to 8 hours.

What do I take for a migraine?

TYLENOL is indicated for temporarily relief of headache pain, not pain due to migraines. Talk to your doctor if your symptoms worsen or persist.

Best medicine for tension headaches?

Tension headaches are a very common type of headache. TYLENOL® helps relieve pain from tension headaches, without irritating the stomach. Rest, hydration, and screen breaks can also help.

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Our Other Brands:Hewyn|Selfship

Tylenol Acetaminophen 650 mg Extended Release Caplets, Fast, Strong Pain Relief, 8 Hour Arthritis Pain Relief, Joint Pain Reliever & Fever Reducer, Long-Lasting Relief, Oral Medicine, 225 Count

Product ID: 22458616

Details

Brand
Tylenol
Item Weight
1.9 Ounces
Item dimensions L x W x H
0.12 x 5 x 5
Product Benefits
Arthritis
Specific Uses For Product
Arthritis

⏳8-hour extended relief

🌿stomach-friendly non-aspirin

💊650mg acetaminophen strength

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€ 56.93

Duties & taxes included

In stock

Sold byAmazon GreeceDelivered byDesertcartCustomer service byDesertcartReturns14 days · 30 with PRO

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Description

⏳💊 Stay ahead of pain with 8-hour unstoppable relief!

POWERFUL 650 MG DOSE - Clinically proven acetaminophen strength for effective pain & fever relief
GENTLE ON YOUR STOMACH - Non-aspirin formula avoids common NSAID irritation
VERSATILE PAIN MANAGEMENT - Targets arthritis, joint pain, headaches, cramps & cold symptoms
DUAL LAYER FAST LASTING RELIEF - Immediate + sustained pain control for up to 8 hours
BULK SUPPLY FOR CONSISTENT COMFORT - 225 caplets ensure you’re always prepared for pain flare-ups

Tylenol 8 Hour Arthritis Pain Relief Extended-Release Caplets deliver a potent 650mg acetaminophen dose in a dual-layer design that provides fast-acting and sustained pain relief for up to 8 hours. This non-aspirin formula is gentle on the stomach and effectively manages arthritis, joint pain, headaches, menstrual cramps, and fever. With 225 caplets per bottle, it offers a reliable, long-lasting solution for adults seeking continuous comfort without frequent dosing.

Specifications

ASIN	B000I09B3Y
ASIN	B000I09B3Y
Active Ingredients	Acetaminophen
Additional Features	Fast-Acting
Age Range Description	Adult
Best Sellers Rank	#235 in Health & Household ( See Top 100 in Health & Household ) #4 in Acetaminophen
Brand Name	Tylenol
Container Type	Bottle
Customer Reviews	4.9 4.9 out of 5 stars (7,827)
Date First Available	September 11, 2006
Dosage Form	Tablets
Global Trade Identification Number	00300450838377
Is Discontinued By Manufacturer	No
Item Dimensions	0.12 x 5 x 5 inches
Item Form	Caplet
Item Weight	1.9 Ounces
Item model number	30045083837
Manufacturer	Johnson & Johnson
Manufacturer	Johnson & Johnson
Model Name	8 Hour Arthritis Pain Relief Extended-Release Tablets 650 mg Acetaminophen
Model Number	30045083837
Net Content Count	225 Count
Number of Items	1
Package Type Name	Bottle
Product Benefits	Arthritis Control
Product Dimensions	0.12 x 5 x 5 inches; 1.9 ounces
Specific Uses For Product	Arthritis
Target Audience	Unisex-Adults
Target Use Body Part	Feet, Hands
UPC	300450838377
Unit Count	225 Count
Warranty Description	No

Reviews

I**4

⭐ Reliable relief that actually lasts

I keep this on hand for joint and general pain, and it’s been consistent every time. 👍 What I liked: Helps take the edge off pain without needing constant re-dosing Extended release lasts several hours as advertised Easy to keep stocked with the larger bottle 👎 What I didn’t love: Doesn’t completely eliminate pain, but definitely makes it manageable ⚖️ Honest verdict: This is a solid, reliable option if you need steady relief throughout the day. I reach for this regularly. Best for: ongoing aches, joint discomfort, general pain relief Skip if: you’re expecting instant or complete pain elimination

1.04.2026

L**E

Works so well after total knee replacement.

I had 2 knee surgeries in 1 year. I stayed on this every 8 hours and it gave me pain relief around the clock. I'm on it 3 months and follow recommended dosage. I've told older friends.

8.04.2026

I**Y

Good price!!

3.03.2026

T**R

Very good product to get you to the next time for your pain medication

I enjoy taking these as a breakthrough pain med. This is a very good product, works very good for me.

15.04.2026

S**R

Wonderful

These work so well

5.04.2026

A**S

Best Acetaminophen

I probably ordered Tylenol more than anything from Amazon. It’s my go to analgesic it does not upset your stomach. I can’t take ibuprofen for that very reason.

15.04.2026

W**N

And it was affordable , the price was good

I'm happy with it is sue's my pain

13.04.2026

G**S

Fast

Works fast

16.04.2026

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