---
product_id: 715574302
title: "Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz"
brand: "zymox"
price: "€ 94.78"
currency: EUR
in_stock: true
reviews_count: 5
category: "Zymox"
url: https://www.desertcart.gr/products/715574302-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats
store_origin: GR
region: Greece
---

# 1.25oz gentle, no pre-cleaning needed LP3 Enzyme System for deep biofilm penetration 1% Hydrocortisone for instant itch relief Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz

**Brand:** zymox
**Price:** € 94.78
**Availability:** ✅ In Stock

## Summary

> 🐾 Clear ears, happy pets—because your furry friend deserves the best!

## Quick Answers

- **What is this?** Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz by zymox
- **How much does it cost?** € 94.78 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.gr](https://www.desertcart.gr/products/715574302-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs-cats)

## Best For

- zymox enthusiasts

## Why This Product

- Trusted zymox brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Fast-Acting Comfort:** 1% Hydrocortisone soothes itching and redness, providing near-instant relief
- • **Pain-Free Application:** No pre-cleaning required—gentle on sensitive ears, perfect for anxious pets
- • **Vet-Trusted Since 1998:** Clinically proven formula trusted by professionals for over two decades
- • **Biofilm-Busting Enzymes:** Patented LP3 Enzyme System penetrates stubborn ear biofilms for lasting relief
- • **All-Age, All-Species Care:** Safe and effective for dogs and cats of every life stage, cruelty-free and USA made

## Overview

Zymox Advanced Formula Otic Plus is a veterinarian-recommended enzymatic ear solution for dogs and cats, featuring a patented LP3 Enzyme System that penetrates biofilms and 1% Hydrocortisone to soothe itching and redness. This 1.25oz formula requires no pre-cleaning, making it a gentle, fast-acting, and cruelty-free choice for pets of all ages.

## Description

Trusted by Veterinarians since 1998. ZYMOX Ear Solution with hydrocortisone aids in managing problematic ears on all animals including dogs and cats of any age. The patented LP3 Enzyme System delivers a potent formula to maximize the power of this product, without traumatic pre-cleaning and application. Otic Plus system works to penetrate deeper into the underlying bacteria's protective biofilm.1% Hydrocortisone is added for comfort. Use once daily for 7 to 14 days. For maintaining clean and healthy ears after the course of Ear Solution, use ZYMOX Ear Cleanser weekly. This product is proudly made in the USA. Animal Cruelty-Free and is never tested on animals. Item dimensions; 1.88"L x 1.13"W x 3.88"H, 1.25 Fluid Ounces (37ml).

Review: great product , great service
Review: Effective Relief for Dog's Itchy Ears

## Features

- Cat and dog ear cleaner, soothes recurrent ear issues, itching and redness, for pets of all ages
- Relief from stubborn ear problem-causing microorganisms that form complex, irritating biofilms
- Gentle formula helps relieve painful ear issues caused by resistant germs, fungi and yeast
- Pet ear solution, no pre-cleaning of painful ears needed; safe, natural alternative to medication
- LP3 Enzyme System to help clear ear exudate; 1% Hydrocortisone for itchy ears

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0066VLPGA |
| Allergen Information | Abalone Free |
| Batteries Included | No |
| Best Sellers Rank | #14,829 in Pet Supplies ( See Top 100 in Pet Supplies ) #49 in Dog Ear Care #374 in Cat Health Supplies |
| Color | Original Version |
| Customer Reviews | 4.7 4.7 out of 5 stars (12,149) |
| Date First Available | 16 October 2013 |
| Item Weight | 36.8 g |
| Item model number | 441125 |
| Number of Items | 1 |
| Pet Life Stage | All Life Stages |
| Pet Type | Cat, Dog, Kitten, Pet, Puppy |
| Product Dimensions | 19.69 x 10.8 x 9.53 cm; 36.85 g |
| Quantity | 1 |
| Size | 55 g |
| Specific Uses | EAR |
| batteries required | No |

## Images

![Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz - Image 1](https://m.media-amazon.com/images/I/512WnsXPqIL.jpg)

## Questions & Answers

**Q: How is Zymox Plus different from Zymox (with the blue label)?  both say 1.0 hydrocortisone.**
A: My veterinarian said just to use the regular Zymox. It’s $10 cheaper and has the exact same ingredient. I looked it up myself. You can see the active ingredient in the inactive ingredient. Everything is the same.

It’s kind of like the namebrand Excedrin. They they packaged their product in different ways. They have Excedrin for headaches Excedrin for migraine. Exactly the same product. A lot of companies do that apparently.

Hope this helps

**Q: how do you get all the wax off the inside of the ears where it flushes out from the ear drops**
A: This is a bit thicker, kind of like the consistency of neosporin, so if your dogs ears are really wax-y right now, I would suggest doing a light cleaning before putting this in the ears. Once you put the zymox into the ear, rub your dogs ears kind of in a circular motion to help massage the solution down into the ear canal, and then just let it sit and do it's thing. Over time there will be less wax build up to clean out before applying the ointment. I now put it in my dogs ears about once every 10 to 15 days, just as maintenance and care, without needing any wax clean up before hand or afterwards.

**Q: Is this supposed to be liquidy/thin like water (not thick)? What I received is a different consistency than the thicker regular zymox I'm used to.**
A: I ordered and received a bottle this week and the solution is much thinner than the previous zymox plus otic-hc advanced formula bottles I've ordered. I haven't used it yet but just by shaking the bottle I can tell it is very liquidy compared to the bottle I have left over. I also compared the boxes and the box I received this week looks different as well. The font is different and the box has a different texture. I also read the paper inside and noticed a major typo on the one I just received. Instead of spelling "externa" they spelled "exernna" 🤦🏽‍♀️ The boxes have different lot numbers and the box that I have already opened has a later expiration date than the box I just received. I hope they didn't send me a knock off. This enzymatic solution usually works wonders on my Boxer and completely cures her ear infections when I use it as directed. I will update you on the effectiveness of the bottle I just received after I use it.

**Q: is this the same as Mometamax 15g**
A: No Different item Mometamax is stronger and is prescription medication.

## Customer Reviews

### ⭐⭐⭐⭐⭐ great product , great service
*by G***S on 13 August 2025*



### ⭐⭐⭐⭐⭐ Effective Relief for Dog's Itchy Ears
*by V***E on 20 January 2026*



### ⭐⭐⭐⭐⭐ Most Effective Ear Treatment Vet Recommended
*by J***I on 3 February 2026*



## Frequently Bought Together

- Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz
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*Product available on Desertcart Greece*
*Store origin: GR*
*Last updated: 2026-02-23*