--- product_id: 15690762 title: "Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets" brand: "life extension" price: "€ 28.50" currency: EUR in_stock: true reviews_count: 11 category: "Life Extension" url: https://www.desertcart.gr/products/15690762-life-extension-optimized-folate-l-methylfolate-heart-and-brain-support store_origin: GR region: Greece --- # Non-GMO, gluten-free, vegetarian 1700 mcg bioactive 5-MTHF folate Supports healthy homocysteine levels Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets **Brand:** life extension **Price:** € 28.50 **Availability:** ✅ In Stock ## Summary > 🧬 Elevate your heart & mind with the folate upgrade you can’t afford to miss! ## Quick Answers - **What is this?** Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets by life extension - **How much does it cost?** € 28.50 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.gr](https://www.desertcart.gr/products/15690762-life-extension-optimized-folate-l-methylfolate-heart-and-brain-support) ## Best For - life extension enthusiasts ## Why This Product - Trusted life extension brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Brainpower Boost:** Optimized 5-MTHF form enhances cognitive function and supports neurotransmitter synthesis for sharper focus and memory. - • **Heart Health Hero:** Clinically-backed folate dosage helps maintain normal homocysteine levels, a key marker for cardiovascular wellness. - • **Superior Absorption:** Up to 7x more bioavailable than standard folic acid, ensuring your body gets the folate it truly needs. - • **Pure & Clean Formula:** Crafted with premium non-GMO, gluten-free, and vegetarian ingredients—because your health deserves the best. - • **Trusted Quality & Transparency:** Made in the USA with rigorous testing and a Certificate of Analysis available for every batch. ## Overview Life Extension Optimized Folate delivers 1700 mcg of the metabolically active 5-MTHF form of folate per vegetarian tablet, supporting cardiovascular health by maintaining healthy homocysteine levels and enhancing cognitive function. This non-GMO, gluten-free supplement offers superior absorption compared to standard folic acid, made with premium ingredients in the USA and backed by scientific research. ## Description Folate helps maintain homocysteine levels within the normal range, which promotes cardiovascular health. And it also supports neurotransmitter synthesis — which in turn helps maintain cognitive abilities. However, not everyone has sufficient activity of the enzyme required to convert folate to its biologically active form, 5-methyltetrahydrofolate, or 5-MTHF. That’s why each vegetarian tablet of Optimized Folate provides 1,700 mcg of the bioactive 5-MTHF form of folate which is up to 7 times more bioavailable than ordinary folic acid. Review: Help support cardiovascular and cognitive health and maintaining healthy homocysteine levels - Excellent product,at a great price. It arrived in great packaging, it arrived exactly on time , there is no damage, product is in date, it had no odor. Not beneficial for energy. The item absorbes well. No known side effects. The idea of this medication is to take when you need support for cardiovascular and cognitive health and maintaining healthy homocysteine levels. Review: Heathy - The quality is great. They work for moods and energy. ## Features - Get a brain boost – Stay proactive about your brain health and support optimal cognitive function with this folate supplement. This 1700 mcg vitamin B formula helps maintain healthy cognition—especially as you age. - Pump up the heart health – This 5-MTHF supplement is a cardiovascular health superstar! Folate helps maintain already-normal homocysteine levels, an important cardiovascular health marker. Folate is a great way to keep heart health in check. - Metabolically active form – 5-MTHF, the metabolically active form of folate, is good for your heart and brain health. But not everyone can convert the dietary form of folate (known as folic acid) into 5-MTHF. This supplement provides folate’s 5-MTHF form. - Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one. - Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B00UD0IPYU | | Age Range Description | Adult | | Allergen Information | Gluten Free | | Best Sellers Rank | #9,747 in Health & Household ( See Top 100 in Health & Household ) #15 in Vitamin B9 (Folic Acid) Supplements | | Brand | Life Extension | | Brand Name | Life Extension | | Color | Off White | | Container Type | Bottle | | Customer Reviews | 4.7 out of 5 stars 3,846 Reviews | | Diet Type | Vegetarian | | Dosage Form | Tablet | | Flavor | Unflavored | | Global Trade Identification Number | 00737870193913 | | Item Dimensions | 2.09 x 2.09 x 3.73 inches | | Item Form | Tablet | | Item Nype Name | L-Methylfolate Supplement | | Item Weight | 0.11 Pounds | | Manufacturer | Life Extension | | Manufacturer Part Number | 01939 | | Material Type Free | Gluten Free, Non GMO | | Model Name | Optimized Folate | | Model Number | 01939 | | Number of Items | 1 | | Primary Supplement Type | Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt] | | Product Benefits | Anti-Aging & Longevity Supplements, Brain Health Support, Heart Health Support | | Special Ingredients | Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt] 1,700 mcg° | | Specific Uses For Product | Delivers 1,700 mcg of the B vitamin folate, Helps maintain already-healthy homocysteine levels, Supports both cardiovascular & cognitive health | | Supplement Formulation | Multi-Supplement | | UPC | 737870193913 | | Unit Count | 100.00 Count | ## Product Details - **Brand:** Life Extension - **Diet Type:** Vegetarian - **Flavor:** Unflavored - **Item Form:** Tablet - **Primary Supplement Type:** Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt] ## Images ![Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets - Image 1](https://m.media-amazon.com/images/I/71vf+u6dkiL.jpg) ## Questions & Answers **Q: It says 1700 mcf DFE of folate, but how of that is actual folic acid equivalent?** A: Hello, We apologize for any confusion. At the end of August of 2020, we updated our Optimized Folate supplement facts section. The amount of folate was updated from 1,000 mcg to 1,700 mcg based on updated FDA labeling guidelines. This change is a result of what the FDA has defined as dietary folate equivalents (DFE). They determined that 0.6 mcg of (6S)-5-methyltetrahydrofolate, calcium salt is equal to 1 mcg DFE. They have also determined that one mcg of naturally occurring folate is equal to one mcg DFE. Their rationale is that this accounts for the greater bioavailability (6S)-5-methyltetrahydrofolate, calcium salt compared to naturally occurring folate. The change to 1,700 mcg in this product allows us to deliver the desired potency in terms of DFE. **Q: What is the expiration date?** A: The expiration date on mine is 7/20/2023, but I bought it over 3 months ago. I have no idea what the expiration date will be on the bottle you’re buying. **Q: Is this Metafolin?** A: Metafolin is a trademarked name for the active form of folate, known as methylfolate. While Optimized Folate doesn't utilize this specific brand, it does include L-Methylfolate. **Q: Is any component of your usa manufactured product sourced from china or india?** A: It's been a very long time since I purchased this product. I no longer have the container and have consumed all of the product. That said, I have since switched to Folic Acid 800 mcg made in Austin Texas and available on Amazon. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Help support cardiovascular and cognitive health and maintaining healthy homocysteine levels *by D***. on April 25, 2026* Excellent product,at a great price. It arrived in great packaging, it arrived exactly on time , there is no damage, product is in date, it had no odor. Not beneficial for energy. The item absorbes well. No known side effects. The idea of this medication is to take when you need support for cardiovascular and cognitive health and maintaining healthy homocysteine levels. ### ⭐⭐⭐⭐⭐ Heathy *by C***N on April 30, 2026* The quality is great. They work for moods and energy. ### ⭐⭐⭐⭐⭐ A Must Have For MTHFR!!! *by H***N on October 29, 2024* I’ve been taking Life Extension Optimized Folate for a while now and couldn’t be happier with the results! This supplement provides 1700 mcg DFE of L-methylfolate, which is significantly more bioavailable than standard folic acid. I’ve noticed a remarkable improvement in my mood and energy levels since incorporating it into my daily routine. The vegetarian tablets are easy to swallow and have no unpleasant taste, making them a breeze to take. I appreciate that they are non-GMO and gluten-free, aligning perfectly with my dietary preferences. Plus, knowing that it helps maintain healthy homocysteine levels gives me peace of mind about my heart health. It’s a must-have for anyone struggling with the MTHFR gene mutation, as it bypasses the conversion issues associated with folic acid. Overall, I highly recommend this product for anyone looking to boost their folate intake effectively! It’s a fantastic value for the quality you receive. ## Frequently Bought Together - Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets - Life Extension TMG 500 mg – Trimethylglycine Supplement – Encourages Healthy Homocysteine Levels – Gluten-free – Non-gmo – Vegetarian – 60 Liquid Vegetarian Capsules - Life Extension Neuro-Mag Magnesium L-Threonate, Magnesium L-threonate, Memory Health, Quick Thinking, Cognitive Health Support, Vegetarian, Non-GMO, 90 Vegetarian Capsules --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.gr/products/15690762-life-extension-optimized-folate-l-methylfolate-heart-and-brain-support](https://www.desertcart.gr/products/15690762-life-extension-optimized-folate-l-methylfolate-heart-and-brain-support) --- *Product available on Desertcart Greece* *Store origin: GR* *Last updated: 2026-07-13*